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Апоптоз і рак: від теорії до практики

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  • user warning: Table './uh231981_yoi/variable' is marked as crashed and should be repaired query: UPDATE variable SET value = 'a:31:{i:0;i:126;i:1;i:64;i:2;i:63;i:3;i:62;i:4;i:61;i:5;i:59;i:6;i:58;i:7;i:57;i:8;i:56;i:9;i:31;i:10;i:30;i:11;i:29;i:12;i:28;i:13;i:25;i:14;i:24;i:15;i:21;i:16;i:16;i:17;i:15;i:18;i:14;i:19;i:13;i:20;i:12;i:21;i:11;i:22;i:10;i:23;i:9;i:24;i:7;i:25;i:6;i:26;i:5;i:27;i:4;i:28;i:3;i:29;i:2;i:30;i:1;}' WHERE name = 'menu_masks' in /home/uh231981/domains/youalib.com/public_html/includes/bootstrap.inc on line 523.
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У монографії узагальнені найновіші відомості про закономірності та механізми загибелі клітин еукаріотичних організмів. Порівнюючи різні форми такої загибелі – апоптоз, який ще називають запрограмованою або фізіологічною смертю клітини, автофагія і некроз – патологічна смерть клітин. У першій главі наведені дані про молекулярні та клітинні механізми апоптозу, а також показана біологічна роль цього процесу в нормі та за різних патологічних станів у людини. У другій главі проведено аналіз різних методів дослідження апоптозу in vitro та in vivo. Їх використання дозволяє точніше виявляти ранні патологічні зміни, адекватно оцінювати стадію захворювання й ефективність проведеної терапії, а також корегувати індивідуальні схеми лікування онкологічних хворих. У третій главі охарактеризовані особливості апоптозу пухлинних клітин, зокрема механізми, які викликають зміни в регуляції апоптозу під час злоякісного росту. Остання глава монографії присвячена перспективам використання препаратів, які впливають на апоптоз та ангіогенез, у протипухлинній терапії. Книга розрахована та фахівців у різних галузях біології та медицини. Вона буде корисною не лише для лікарів-онкологів, але й для широкого кола читачів, які цікавляться новинками в галузі природничих наук. Табл. 17.Мал. 45. Бібліогр.: гл. 1 (250 посилань), гл. 2 (208 посилань), гл.3( 504 посилання), гл.4 (342 посилання).